Assessment of anti-inflammatory of stem extract of Musa balbisianain wound healing on rats (Rattus norvegicus)

Karimah, Fadhilah Nurul, Mashudi, Sugeng, Nurhidayat, Saiful, Azzarin, Auliya Wanda and Amanah, Nuraini Khoirotun (2024) Assessment of anti-inflammatory of stem extract of Musa balbisianain wound healing on rats (Rattus norvegicus). Malahayati International Journal of Nursing and Health Science, 7 (1). pp. 46-51. ISSN ISSN 2620-9152 (Print) ISSN 2621-4083 (Online)

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Abstract

Background: Balbisiana is a plant that contains flavonoids, which are antioxidants with high anti-inflammatory activity. This antioxidant activity can help the wound-healing process. Purpose: To determine the anti-inflammatory effect of balbisiana extract to help wound healing. Method: The study used 15 rats, which were divided into five groups: a positive control group, a negative control group, a 10% balbisiana extract group, a 20% balbisiana extract group, and a 40% balbisiana extract group. Statistical analysis was performed using the Shapiro-Wilk test to test the normality of the distribution of continuous quantitative data. Levene's test was then used to assess the statistical homogeneity of variance between groups. Welch's One-Way ANOVA was used to analyze the data. Post-hoc analysis was performed using the Games-Howell test. Results: The results of the study showed that balbisiana extract had significant anti-inflammatory activity, especially at a concentration of 40%. This was demonstrated by the results of the study, which showed that rats treated with 40% balbisiana extract had significantly improved wound healing compared to the control groups. Conclusion: This study shows that balbisiana extract has anti-inflammatory activity in helping the wound healing process.

Item Type:	Article
Uncontrolled Keywords:	Anti-Inflammatory, Balbisiana, Wound Healing
Subjects:	R Medicine > RT Nursing
Divisions:	Faculty of Health Sciences
Depositing User:	Library Umpo
Date Deposited:	04 Apr 2024 06:38
Last Modified:	04 Apr 2024 06:42
URI:	http://eprints.umpo.ac.id/id/eprint/13840

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