Assessment of anti-inflammatory of stem extract of Musa balbisiana in wound healing on rats (Rattus norvegicus)

Karimah, Fadhilah Nurul, Mashudi, Sugeng, Nurhidayat, Saiful, Azzarin, Auliya Wanda and Amanah, Nuraini Khoirotun (2024) Assessment of anti-inflammatory of stem extract of Musa balbisiana in wound healing on rats (Rattus norvegicus). Assessment of anti-inflammatory of stem extract of Musa balbisiana in wound healing on rats (Rattus norvegicus), 7 (1). pp. 46-51. ISSN 2621-4083

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Abstract

Background: Balbisiana is a plant that contains flavonoids, which are antioxidants with high anti-inflammatory
activity. This antioxidant activity can help the wound-healing process.
Purpose: To determine the anti-inflammatory effect of balbisiana extract to help wound healing.
Method: The study used 15 rats, which were divided into five groups: a positive control group, a negative control
group, a 10% balbisiana extract group, a 20% balbisiana extract group, and a 40% balbisiana extract group.
Statistical analysis was performed using the Shapiro-Wilk test to test the normality of the distribution of
continuous quantitative data. Levene's test was then used to assess the statistical homogeneity of variance
between groups. Welch's One-Way ANOVA was used to analyze the data. Post-hoc analysis was performed
using the Games-Howell test.
Results: The results of the study showed that balbisiana extract had significant anti-inflammatory activity,
especially at a concentration of 40%. This was demonstrated by the results of the study, which showed that rats
treated with 40% balbisiana extract had significantly improved wound healing compared to the control groups.
Conclusion: This study shows that balbisiana extract has anti-inflammatory activity in helping the wound healing
process.

Item Type:	Article
Uncontrolled Keywords:	Anti-Inflammatory; Balbisiana; Wound Healing.
Subjects:	L Education > L Education (General) L Education > LB Theory and practice of education > LB1501 Primary Education
Divisions:	Faculty of Health Sciences
Depositing User:	fik . userfik
Date Deposited:	06 Aug 2024 02:17
Last Modified:	08 Jan 2025 04:03
URI:	https://eprints.umpo.ac.id/id/eprint/14150

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