Assessment of anti-inflammatory of stem extract of Musa balbisiana in wound healing on rats (Rattus norvegicus)

Background: Balbisiana is a plant that contains flavonoids, which are antioxidants with high anti-inflammatory
activity. This antioxidant activity can help the wound-healing process.
Purpose: To determine the anti-inflammatory effect of balbisiana extract to help wound healing.
Method: The study used 15 rats, which were divided into five groups: a positive control group, a negative control
group, a 10% balbisiana extract group, a 20% balbisiana extract group, and a 40% balbisiana extract group.
Statistical analysis was performed using the Shapiro-Wilk test to test the normality of the distribution of
continuous quantitative data. Levene's test was then used to assess the statistical homogeneity of variance
between groups. Welch's One-Way ANOVA was used to analyze the data. Post-hoc analysis was performed
using the Games-Howell test.
Results: The results of the study showed that balbisiana extract had significant anti-inflammatory activity,
especially at a concentration of 40%. This was demonstrated by the results of the study, which showed that rats
treated with 40% balbisiana extract had significantly improved wound healing compared to the control groups.
Conclusion: This study shows that balbisiana extract has anti-inflammatory activity in helping the wound healing
process.